Clinically proven AHA or clinically proven? Yes.

With non-prescription AmLactin® Alpha-Hydroxy Skin Care products, you’ve got the best of both worlds. Effective at exfoliating and hydrating the skin, our formulas also contain emollients and humectants that help retain the skin’s natural moisture and draw water to the skin so it looks and feels soft and smooth. In fact, AmLactin® Moisturizing Body Lotion with 12% lactic acid, a clinically proven AHA, is dermatologist recommended.

Then there’s the clinically proven, patented ULTRAPLEX® formula in AmLactin® Ultra Hydrating Body Cream and our AmLactin® Foot Cream. As grand as that sounds, most likely you came to this page seeking facts best demonstrated in clinical studies with lots of charts and footnotes. So, without further ado…

Clinically proven superior in hydrating severe dry skin.1

When it comes to impressive results in a clinical trial, AmLactin® Ultra Hydrating Body Cream (formerly AmLactin XL®) with the patented ULTRAPLEX® formula repeatedly finished ahead of 40% urea cream in key categories.

Proven significantly superior to 40% urea cream* in hydrating skin1

Chart1

Expert grader evaluations. Scale of 0-8, with 0=no dryness; 8=severe scaling, fissuring. N=25.

* Carmol® 40 Cream.
† P<0.000001 compared to 40% urea cream.

  • AmLactin® Ultra Hydrating Body Cream was proven both effective in moisturizing and well tolerated1
  • Even at 2 weeks after last application, AmLactin® Ultra Hydrating Body Cream maintained better visual dryness scores than 40% urea cream‡1

Regression on day 21.
Reference: 1. Data on file. Upsher-Smith Laboratories, Inc.


Proven significantly superior to 40% urea cream* in improving a wide range of dry skin characteristics1

Chart 2

Subject self-assessments at day 14. Scale of 0-10. Dryness: 0=no sign of dryness; 10=extremely dry. Smoothness: 0=extremely smooth; 10=extremely rough. Softness: 0=extremely soft; 10=not soft at all. Texture: 0=no scaling, cracking, or fissuring; 10=very coarse scaling, cracking, or fissuring. N=25.

* Carmol® 40 Cream.
P<0.005 compared to 40% urea cream.
Reference: 1. Data on file. Upsher-Smith Laboratories, Inc.


The majority of patients agreed1:

Chart3

Subject assessments of product satisfaction, day 21. N=25.

Reference: 1. Data on file. Upsher-Smith Laboratories, Inc.


Lactic acid. Studies worth studying.

Effect of lactic acid isomers on keratinocyte ceramide synthesis, stratum corneum lipid levels and stratum corneum barrier function

By A.V. Rawlings, A. Davies, M. Carlomusto, S. Pillai, K. Zhang, R. Kosturko, P. Verdejo, C. Feinberg, L. Nguyen, P. Chandar

Alpha-hydroxy acids are effective agents for the treatment of…
Read more


Epidermal and dermal effects of topical lactic acid.

By Walter P. Smith, PhD

The purpose was to examine whether treatment with 5% and 12% lactic acid produces different cosmetic results…
Read more


Effects of alpha-hydroxy acids on photoaged skin: a pilot clinical, histologic, and ultrastructural study.

By C.M. Ditre, T.D. Griffin, G.F. Muphy, H. Sueki, B. Telegan, W.C. Johnson, R.J. Yu, E.J. Van Scott

Treatment with AHAs caused an approximate 25% increase in skin thickness…
Read more


Carmol® 40 Cream is a registered trademark of Doak Dermatologics, a subsidiary of Bradley Pharmaceuticals, Inc.

Sunburn Alert: This product contains an alpha-hydroxy acid (AHA) that may increase your skin’s sensitivity to sunburn. Be sun smart: use sunscreen, wear protective clothing, and limit sun exposure while using this product and for a week afterward.

In exchange for allowing us to share their stories, the featured women received a gift basket including AmLactin® products.


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